The first quinine brought to Java in 1854 from the slopes of Andes in South America and became invasive in the highland. The study to clarify the invasion of quinine to the montane forest of Java was conducted in 2011 and 2015 at three sites in Mt. Gede Pangrango National Park (GPNP) and one site in Mt. Tangkuban Perahu Nature Reserve (TPNR), West Java. At each site, a belt transect with 10 meter width from forest edge to its interior to record size of Cinchona. Trees of all species >1.3m in height were tagged and measured in the five plots of 10mx30m in quinines origin (quinines plantations/ ex-plantations) and in the natural forests. Two species of Cinchona were found: C. pubescens and C. calisaya. The former is stated as one of 100 of the most invasive species by IUCN, and used as rootstocks of grafts of the latter in the plantations. In belt in southern part of GPNP, number of C. pubescence changed from 164 in 2011 to 831 in 2015 and 12 individuals of C. pubescens expanded 10m into forest though we could not find significant change in other sites. The growth rates of the two species in the plots were not significantly different: 0.09 cm/ year in DBH and 0.12 m/ year in H in C. pubescens and 0.14 cm/ year in DBH and 0.13 m/ year in H in C. calisaya.